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Will Neuroimaging help us understand Alzheimer's disease? William Jagust page P1 Full Text | Full-Text PDF (138 KB)
Do the biomarker findings fit the hypotheses? Roger Nitsch page P1 Full Text | Full-Text PDF (138 KB)
ADNI PiB Studies Chester A. Mathis page P1 Full Text | Full-Text PDF (144 KB)
AIBL (Australian Imaging, Biomarkers and Lifestyle) flagship study of aging Victor L. Villemagne pages P1-P2 Full Text | Full-Text PDF (250 KB)
PET Amyloid imaging and cognition in patients with Alzheimer's disease, Mild Cognitive Impairment (MCI) and healthy controls: a European multicenter study Agneta Nordberg, Juha Rinne, Alexander Drzezga, David J. Brooks, Rik Vandenberghe, Daniela Perani, Ove Almkvist, Noora Scheinin, Timo Grimmer, Aren Okello, Koen Van Laere, Rainer Hinz, Stephen F. Carter, Elke Kalbe, Karl Herholz page P2 Full Text | Full-Text PDF (134 KB)
White Matter Imaging in Understanding Aging and Alzheimer's Disease Charles DeCarli page P2 Full Text | Full-Text PDF (135 KB)
Tracking disease progression with volumetric MRI Nick Fox page P3 Full Text | Full-Text PDF (46 KB)
Integrating MR techniques to study Alzheimer's disease Frederik Barkhof page P3 Full Text | Full-Text PDF (45 KB)
Genetic predictors of 12-month change in MRI hippocampal volume in the Alzheimer's Disease Neuroimaging Initiative cohort: Analysis of leading candidates from the AlzGene database Andrew J. Saykin, Li Shen, Shannon L. Risacher, Sungeun Kim, Kwangsik Nho, John D. West, Tatiana M page P3 Full Text | Full-Text PDF (42 KB)
Neural underpinnings of autobiographical memory retrieval in Alzheimer's disease Olga Meulenbroek, Roy P.C. Kessels, Marcel G.M. Olde Rikkert, Mark Rijpkema, Guillén Fernández page P3 Full Text | Full-Text PDF (45 KB)
From mild cognitive impairment to Alzheimer's disease: comparisons of metabolic and structural brain alteration evolutions Nicolas Villain, Marine Fouquet, Brigitte Landeau, Mezenge Florence, Vincent de la Sayette, Fausto Viader, Jean-Claude Baron, Francis Eustache, Béatrice Desgranges, Gaël Chételat pages P3-P4 Full Text | Full-Text PDF (379 KB)
Patterns of brain atrophy in frontotemporal dementia with mutations in MAPT or PGRN Jennifer L. Whitwell, Clifford R. Jack, Bradley F. Boeve, Matthew L. Senjem, Rosa Rademakers, Matthew Baker, Robert J. Ivnik, David S. Knopman, Zbigniew K. Wszolek, Ronald C. Petersen, Keith A. Josephs page P4 Full Text | Full-Text PDF (360 KB)
Twelve-Month follow-up study of Fractional Anisotropy changes in Mild Cognitive Impairment compared to healthy elderly subjects Yuttachai Likitjaroen, Thomas Meindl, Maximilian Wagner, Katharina Bürger, Harald Hampel, Stefan J. Teipel page P5 Full Text | Full-Text PDF (249 KB)
Prevalence of beta-amyloid plaques in a nondemented population using [11C]PIB and PET: Impact of APOE genotype Mark A. Mintun, Cathy M. Roe, Yvette I. Sheline, Alison M. Goate, Chengjie Xiong, Andrei G. Vlassenko, John C. Morris page P5 Full Text | Full-Text PDF (247 KB)
CSF Abeta and Tau associations with 3-D hippocampal radial distance mapped in 282 ADNI subjects Liana G. Apostolova, Kristy S. Hwang, Amity E. Green, Sona Babakchanian, Jonathan H. Morra, Jeffrey L. Cummings, Arthur W. Toga, John Trojanowski, Lesley Shaw, Clifford R. Jack, Michael W. Weiner, Paul M. Thompson page P6 Full Text | Full-Text PDF (139 KB)
Long-term effect of phenserine treatment in Alzheimer patients as assessed by PET and CSF biomarkers Ahmadul Kadir, Henrik Zetterberg, Niels Andreasen, Ove Almkvist, Anders Wall, Anton Forsberg, Kaj Blennow, Bengt Långström, Agneta Nordberg page P6 Full Text | Full-Text PDF (139 KB)
Cellular and animal model Jacques O. Lundja page P6 Full Text | Full-Text PDF (138 KB)
Links between cerebral atrophy, behavioral alterations and neuropathological changes in mouse lemur primates Marc Dhenain, Audrey Kraska, Nadine Mestre-Frances, Olene Dorieux, Fanny Petit, Emmanuel Bourrin, Anne-Sophie Herard, Evelyne Chenu, Andreas Volk, Martine Perret, Philippe Hantraye, Fabienne Aujard, Jean-Luc Picq page P7 Full Text | Full-Text PDF (44 KB)
Synthetic Abeta 1-40 oligomers impair recognition memory in mice Claudia Balducci, Massimo Messa, Laura Colombo, Mario Salmona, Gianluigi Forloni page P7 Full Text | Full-Text PDF (44 KB)
The first Third-generation Alzheimer mouse, PLB1: An 18F-FDG-PET study Marco Mingarelli, Andy Welch, Marlene Arthur, Hong Wan, Gernot Riedel, Bettina Platt page P7 Full Text | Full-Text PDF (44 KB)
The effect of the PPAR gamma agonist rosiglitazone on age-related changes in grey matter magnetic resonance relaxometry in the rat Christoph W. Blau, Thelma R. Cowley, Joan B. O'Sullivan, Raasay S. Jones, Christian M. Kerskens, Marina A. Lynch pages P7-P8 Full Text | Full-Text PDF (162 KB)
In vivo amyloid plaque detection using contrast-enhanced magnetic resonance microscopy in transgenic mice Alexandra Petiet, Anne Bertrand, Christopher Wiggins, Diane Houitte, Thomas Debeir, Thomas Rooney, Marc Dhenain page P8 Full Text | Full-Text PDF (143 KB)
Memory loss in young APPswe/PS1dE9 mice and associated changes in brain metabolism analyzed using a 3-D voxel-based approach Anne-Sophie Hérard, Thierry Delzescaux, Sylvie Cornet, Jessica Lebenberg, Pierre-Etienne Chabrier, Philippe Hantraye, Marc Dhenain pages P8-P9 Full Text | Full-Text PDF (163 KB)
Alterations of brain glucose metabolism in aged APP/PS1 mice: An original voxel-based statistical analysis using BrainRAT and SPM Anne-Sophie Hérard, Albertine Dubois, Nicolas Souedet, Benoît Delatour, Philippe Hantraye, Marc Dhenain, Thierry Delzescaux page P9 Full Text | Full-Text PDF (44 KB)
In vivo optical and PET detections of fibrillar tau lesions in a mouse model of tauopathies Masahiro Maruyama, Jun Maeda, Bin Ji, Ming-Rong Zhang, Takashi Okauchi, Maiko Ono, Satoko Hattori, John Q. Trojanowski, Virginia M.-Y. Lee., Toshimitsu Fukumura, Makoto Higuchi, Tetsuya Suhara page P9 Full Text | Full-Text PDF (45 KB)
Diagnostic utility of platelet amyloid precursor protein ratio, red blood cells and plasma beta amyloid (Aβ 1-42) levels in late-onset Alzheimer's disease Ben Ashok, B'joe Baben, Vasudevan Devanathan, Senthil Kumar, Jeyakumar Rajadhas pages P9-P10 Full Text | Full-Text PDF (66 KB)
A peripheral diagnostic for Alzheimer's disease with 100% specificity and 94% sensitivity in preliminary testing Paul D. Coleman, Diego Mastroeni, Andrew Grover, Joseph Rogers page P10 Full Text | Full-Text PDF (46 KB)
A case report of Alzheimer's disease with presenilin-1 mutation (Met233Leu) showing a new phenotype Masahiko Takaya, Hiroaki Kazui, Koji Ikezawa, Ryu Kurimoto, Kohichi Yamamoto, Takashi Morihara, Ryouhei Ishii, Hiromasa Tokunaga, Masatoshi Takeda page P10 Full Text | Full-Text PDF (46 KB)
The AIBL study: Baseline data from a multicenter, prospective longitudinal study of ageing in 1,100 volunteers Cassandra Szoeke, Kathryn A. Ellis, Ashley Bush, David Darby, Daniela De Fazio, Jonathan Foster, Peter Hudson, Nicola Lautenschlager, Nat Lenzo, Ralph Martins, Paul Maruff, Colin Masters, Andrew Milner, Kerryn Pike, Christopher Rowe, Greg Savage, Kevin Taddei, Victor Villemagne, Michael Woodward, David J. Ames page P10 Full Text | Full-Text PDF (46 KB)
The functional impact of cerebral white matter hyperintensities in the elderly Melissa E. Murray, Matthew L. Senjem, John H. Hollman, Stephen Weigand, Dennis W. Dickson, Ronald C. Petersen, Clifford R. Jack pages P10-P11 Full Text | Full-Text PDF (62 KB)
Clinical presentations of patients attending a dementia clinic in Kingston, Jamaica Loraine A. Barnaby, Clayton A. Sewell, Garth Lipps page P11 Full Text | Full-Text PDF (41 KB)
Predicting the risk for Alzheimer's disease using functional MRI Marian van der Meulen, Cécile Lederrey, Patrik Vuilleumier, Sophie Schwartz, Frédéric Assal page P11 Full Text | Full-Text PDF (41 KB)
Subtypes of MCI and their progression to particular types of dementia: A community-based prospective neuro-imaging study Jiro Kida, Fumio Yamashita, Chiine Kodama, Chiaki Ikejima, Sho Takahashi, Miho Ota, Nemoto Kiyotaka, Katsuyosyi Mizukami, Takashi Asada pages P11-P12 Full Text | Full-Text PDF (158 KB)
Diffusion tensor imaging characteristics of amnestic and non-amnestic mild cognitive impairment Kejal Kantarci, Ramesh T. Avula, Matthew L. Senjem, Ali R. Samikoglu, Maria M. Shiung, Scott A. Przybelski, Stephen D. Weigand, Heidi A. Ward, Prashanthi Vemuri, David S. Knopman, Bradley F. Boeve, Ronald C. Petersen, Clifford R. Jack page P12 Full Text | Full-Text PDF (142 KB)
Voxel-based morphometry of amnestic mild cognitive impairment and Alzheimer's disease Yi He, Mei-Yan Zhang, Kevin Head, Daniel Chang, Huishu Yuan, Min-Ying Su, Xin Yu, Huali Wang pages P12-P13 Full Text | Full-Text PDF (295 KB)
3-D mapping of episodic memory and executive function in late-onset depression Huali Wang, Na Zhang, Mei-Yan Zhang, Jing Liao, Daniel Chang, Huishu Yuan, Min-Ying Su, Xin Yu page P13 Full Text | Full-Text PDF (178 KB)
Cognitive function of patients with partial anterior circulation infarct and amnestic mild cognitive impairment Mei-Yan Zhang, Qiong Yang, Xin Yu, Na Liu, Dongsheng Fan, Huali Wang page P13 Full Text | Full-Text PDF (178 KB)
The bimodality of healthy ageing: How do the differing profiles of healthy controls compare to patients with mild cognitive impairment? David J. Ames, Paul Maruff, Greg Savage, Jonathan Foster, David Darby, Kerryn Pike, Eleftheria Kotsopoulos, Daniela De Fazio, Christopher Rowe, Cassandra Szoeke, Colin Masters, Ralph Martins, Paul Hudson, Andrew Milner, Kathryn A. Ellis page P14 Full Text | Full-Text PDF (49 KB)
Challenging tests of memory are more sensitive to detect effects of amyloid deposition in normal elderly subjects Meghan T. Frey, John A. Becker, Jacqueline Maye, Trey Hedden, Jeremy Carmasin, Lauren E. Olson, Angel Mehta, Sarah E. Rastegar, Keith A. Johnson, Herman Buschke, Reisa A. Sperling, Dorene M. Rentz page P14 Full Text | Full-Text PDF (49 KB)
Diagnostic usefulness of verbal fluency test in dementia patients with a one-year follow up Ho-Won Lee page P14 Full Text | Full-Text PDF (49 KB)
Shanghai community brain health initiative pilot study: Neuropsychological results Qianhua Zhao, Ding Ding, Qihao Guo, James A. Mortimer, Cathleen I. Copenhaver, David Salmon, Douglas Galasko, Charles DeCarli, Qi Dai, Ron Petersen, Yougui Wu, Zhen Hong, Amy R. Borenstein pages P14-P15 Full Text | Full-Text PDF (63 KB)
Biomarker screening for Alzheimer's disease: When to screen and how often? Kristin Kahle-Wrobleski, Nick Furiak, Robert Klein, Timothy Klein, Eric Siemers page P15 Full Text | Full-Text PDF (38 KB)
New metabolic understanding into innovative strategies for early diagnostics and therapy of Alzheimer's disease Ivan V. Fedoriv, Anna Fedorova page P15 Full Text | Full-Text PDF (39 KB)
Abnormal motor symptoms of Alzheimer's disease are associated with regional volume loss in frontal lobes and cerebellar hemispheres: A Voxel-Based Morphometric study Hee-Jin Kim, Ha-Neul Lee, Seok-Jae Kang, Heui-Kyoung Park, Seung Hyun Kim, Seol-Heui Han pages P15-P16 Full Text | Full-Text PDF (318 KB)
Differential diagnosis of neurodegenerative dementias using structural MRI Prashanthi Vemuri, Kejal Kantarci, Matthew L. Senjem, Jeffrey L. Gunter, Jennifer L. Whitwell, Keith A. Josephs, David S. Knopman, Bradley F. Boeve, Tanis J. Ferman, Dennis W. Dickson, Ronald C. Petersen, Clifford R. Jack page P16 Full Text | Full-Text PDF (302 KB)
Comparison of Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18F-FDG) PET in patients with Alzheimer's disease, Mild Cognitive Impairment and healthy controls Davangere P. Devanand, Arthur Mikhno, Gregory H. Pelton, Katrina Cuasay, J.S. Dileep Kumar, Neil Upton, Robert Lai, Roger Gunn, Vincenzo Libri, J. John Mann, Ramin V. Parsey pages P16-P17 Full Text | Full-Text PDF (326 KB)
PiB negative dementia: Pitfall of clinical diagnosis of Alzheimer's disease Hiroyuki Shimada, Suzuka Ataka, Jun Takeuchi, Jyoji Kawabe, Susumu Shiomi, Hiroshi Mori, Takami Miki, Makoto Shigematsu, Yasuhiro Wada, Yasuyoshi Watanabe, Aki Nakanishi page P17 Full Text | Full-Text PDF (46 KB)
Alzheimer's Disease (AD) and Lewy bodies Dementia (LBD) differential diagnosis: a 123Ioflupane SPECT study Susanna Nuvoli, Antonio Nieddu, Anthony Rotondo, Renata Salvo, Francesca Chessa, Angela Spanu, Giuseppe Madeddu page P17 Full Text | Full-Text PDF (46 KB)
Dementia differential: adding visual-semiquantitative evaluation to a quantitative method for reporting brain SPECT: Comparison between two institutions Wolfgang Staffen, Dan G. Pavel, Steven R. Best, Yu-Ching Chang, Harald Zauner, Jürgen Bergmann pages P17-P18 Full Text | Full-Text PDF (177 KB)
PiB PET Classification: A model to determine those who are at risk of developing Alzheimer's disease Jurgen Fripp, Victor L. Villemagne, Pierrick Bourgeat, Parnesh Raniga, Oscar Acosta, Cassandra Szoeke, Sebastien Ourselin, David Ames, Kathryn A. Ellis, Colin L. Masters, Christopher C. Rowe, Olivier Salvado page P18 Full Text | Full-Text PDF (154 KB)
Can hippocampal or temporal horn atrophy rates predict future conversion to Alzheimer's disease? Kate Macdonald, Kelvin K. Leung, Casper Nielsen, Sebastien Ourselin, Michael W. Weiner, Norbert Schuff, Josephine Barnes, Nick C. Fox pages P18-P19 Full Text | Full-Text PDF (240 KB)
MRI validation of the NINDS-CSN proposed neuropsychological assessment protocol for vascular cognitive impairment Christopher M. Murphy, Joe Zhou, Simon J. Graham, Nancy J. Lobaugh, Novena Rangwala, Chris J.M. Scott, Fuqiang Gao, Sandra E. Black, David L. Nyenhuis, Donald T. Stuss, Anoop Ganda, Mira N. Rizkalla, Laura Pedelty, Elizabeth Gery, Kie Honjo, Glenn T. Stebbins page P19 Full Text | Full-Text PDF (109 KB)
Correlation between white matter lesions progression and cognitive decline in patients with Alzheimer's disease, mixed dementia, vascular dementia and normal elderly persons in prospective study Stanislav Sutovsky, Augustin Durkovsky, Peter Turcani pages P19-P20 Full Text | Full-Text PDF (249 KB)
Interrelation between gray and white matter alterations in Alzheimer's Disease and Frontotemporal Dementia Yu Zhang, Norbert Schuff, Christopher Ching, Duygu Tosun, Marzieh Nezamzadeh, Wang Zhan, Howard J. Rosen, Joel H. Kramer, Maria Luisa Gorno-Tempini, Bruce L. Miller, Michael W. Weiner page P20 Full Text | Full-Text PDF (163 KB)
Measurement of grey matter water diffusion in the clinical variants of frontotemporal lobar degeneration and Alzheimer's disease Jennifer L. Whitwell, Ramesh Avula, Matthew L. Senjem, Kejal Kantarci, Ali Samikoglu, Stephen D. Weigand, Heidi A. Ward, Keith A. Josephs, Prashanthi Vemuri, David S. Knopman, Bradley F. Boeve, Ronald C. Petersen, Clifford R. Jack page P20 Full Text | Full-Text PDF (163 KB)
The application of partial-volume correction to Alzheimer's disease discrimination Benjamin A. Thomas, Lennart Thurfjell, Juha O. Rinne, Sebastien Ourselin, Brian Hutton pages P20-P21 Full Text | Full-Text PDF (249 KB)
3-D mapping of associations amongst amyloid-PET and CSF biomarkers and hippocampal morphology John P. Andrawis, Kristy S. Hwang, Amity E. Green, Sona Babakchanian, Jonathan H. Morra, Jeffrey L. Cummings, Arthur W. Toga, John Q. Trojanowski, Leslie M. Shaw, Clifford R. Jack, Michael W. Weiner, Paul M. Thompson, Liana G. Apostolova page P21 Full Text | Full-Text PDF (110 KB)
Baseline and longitudinal patterns of brain atrophy in MCI patients and their use in prediction of short-term conversion to Alzheimer's disease: Results from ADNI Christos Davatzikos pages P21-P22 Full Text | Full-Text PDF (235 KB)
Reduction of cortical acetylcholine esterase in mild cognitive impairment: Consistency across centers and PET methods Karl Herholz, Christoph Hohmann, Ioana Florea, Andrea Varrone, Cathleen Haense, Roman Krais, Valentina Garibotto, Elke Kalbe, Alessandra Bertoldo, Daniela Perani, Stefan Vollmar, Wolf-Dieter Heiss page P22 Full Text | Full-Text PDF (148 KB)
Imaging of amyloid plaques and cerebral glucose metabolism in amnestic mild cognitive impairment Il Han Choo, Dong Young Lee, Yu Kyeong Kim, Su Jin Kim, Jae Sung Lee, Dong Soo Lee, Ki Woong Kim, Jin Hyeong Jhoo, Jong Choul Youn, Jee Wook Kim, Shin Young Park, Jong Inn Woo page P22 Full Text | Full-Text PDF (148 KB)
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