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Perspectives
Challenges to demonstrating disease-modifying effects in Alzheimer’s disease clinical trials Jeffrey L. Cummings pages 263-271 Abstract | Full Text | Full-Text PDF (229 KB)
Commentary on “Challenges to demonstrating disease-modifying effects in Alzheimer’s disease clinical trials” Paul S. Aisen pages 272-274 Full Text | Full-Text PDF (78 KB)
Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery Dale Schenk, Maria C. Carrillo, John Q. Trojanowski pages 275-281 Abstract | Full Text | Full-Text PDF (580 KB)
Commentary on “Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.” Atorvastatin’s effect in Alzheimer’s dementia (LEADe) study Judith Hey-Hadavi, LEADe investigators pages 282-283 Full Text | Full-Text PDF (65 KB)
Commentary on “Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.” Pleiotropic approaches to Alzheimer’s and other diseases of aging Greg M. Cole, Sally A. Frautschy pages 284-286 Full Text | Full-Text PDF (211 KB)
Commentary on “Optimal design of clinical trials for drugs designed to slow the course of Alzheimer℉s disease.” Biochemical biomarkers of late-life dementia Christopher M. Clark, Domenico Pratico, Lesley M. Shaw, Susan Leight, Sharon X. Xie, Amy Gu, Virginia M.-Y. Lee, John Q. Trojanowski pages 287-293 Full Text | Full-Text PDF (141 KB)
Commentary on “Perspective on a pathogenesis and treatment of Alzheimer’s disease.” Therapeutic strategies for Alzheimer’s disease: The need for a new era of innovation Mark A. Smith, George Perry pages 294-295 Full Text | Full-Text PDF (63 KB)
Featured Articles
Structural MRI discriminates individuals with Mild Cognitive Impairment from age-matched controls: A combined neuropsychological and voxel based morphometry study Mehul A. Trivedi, Allison K. Wichmann, Britta M. Torgerson, Michael A. Ward, Taylor W. Schmitz, Michele L. Ries, Rebecca L. Koscik, Sanjay Asthana, Sterling C. Johnson pages 296-302 Abstract | Full Text | Full-Text PDF (314 KB)
Independent contributions of neural and “higher-order” deficits to symptoms in Alzheimer’s disease: A latent variable modeling approach Rochelle E. Tractenberg, Paul S. Aisen, Myron F. Weiner, Jeffrey L. Cummings, Gregory R. Hancock pages 303-313 Abstract | Full Text | Full-Text PDF (186 KB)
Factors associated with use of medications with potential to impair cognition or cholinesterase inhibitors among Alzheimer’s disease patients Edward D. Huey, Joy L. Taylor, Pauline Luu, John Oehlert, Jared R. Tinklenberg pages 314-321 Abstract | Full Text | Full-Text PDF (133 KB)
Meeting Report
Common threads in neurodegenerative disorders of aging M. Flint Beal, Ella Bossy-Wetzel, Steven Finkbeiner, Gary Fiskum, Benoit Giasson, Carl Johnson, Zaven S. Khachaturian, Virginia M.-Y. Lee, David Nicholls, Hemachandra Reddy, Ian Reynolds, David B. Teplow, Leon J. Thal, John Q. Trojanowski, Dominic M. Walsh, Ronald Wetzel, Nancy S. Wexler, Anne B. Young, Lisa Bain pages 322-326 Full Text | Full-Text PDF (86 KB)
Research News
Dementia diagnosis, treatment, and research with American Indians Myron F. Weiner, Roger N. Rosenberg, Doris Svetlik, Margaret Higgins, Kyle Womack, Carey Fuller, Laura H. Lacritz, C. Munro Cullum pages 327-329 Full Text | Full-Text PDF (67 KB)
Author Index to Volume 2 pages 330-331 Full-Text PDF (61 KB)
Key Word Index to Volume 2 pages 332-333 Full-Text PDF (60 KB)
ALZHEIMER'S ASSOCIATION Update
Alzheimer’s Association Update page 334 Full Text | Full-Text PDF (48 KB)
Frontmatter
Subscriber information page page A2 Full Text | Full-Text PDF (40 KB)
Contents page A3 Full Text | Full-Text PDF (40 KB)
Contents page A4 Full Text | Full-Text PDF (26 KB)
Editorial board page A5 Full-Text PDF (36 KB)
Alzheimer’s Association Medical and Scientific Advisory Council page A6 Full-Text PDF (32 KB)
Information for Authors pages A7-A9 Full Text | Full-Text PDF (67 KB)
Alzheimer’s Association: 2006 Research Grants and Initiatives pages A11-A16 Full Text | Full-Text PDF (61 KB)
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