Current Issue January 2012, Vol. 8, No. 1

Featured Articles

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
January 2012 (Vol. 8 | No. 1 | Pages 1-13)
Bradley T. Hyman, Creighton H. Phelps, Thomas G. Beach, Eileen H. Bigio, Nigel J. Cairns, Maria C. Carrillo, Dennis W. Dickson, Charles Duyckaerts, Matthew P. Frosch, Eliezer Masliah, Suzanne S. Mirra, Peter T. Nelson, Julie A. Schneider, Dietmar Rudolf Thal, Bill Thies, John Q. Trojanowski, Harry V. Vinters, Thomas J. Montine
Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative
January 2012 (Vol. 8 | No. 1 | Pages 65-73)
Hugo Vanderstichele, Mirko Bibl, Sebastiaan Engelborghs, Nathalie Le Bastard, Piotr Lewczuk, Jose Luis Molinuevo, Lucilla Parnetti, Armand Perret-Liaudet, Leslie M. Shaw, Charlotte Teunissen, Dirk Wouters, Kaj Blennow
[123I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography brain imaging in the diagnosis of dementia with Lewy bodies
January 2012 (Vol. 8 | No. 1 | Pages 74-83)
Zuzana Walker, Jeffrey L. Cummings
Mild cognitive impairment: Disparity of incidence and prevalence estimates
January 2012 (Vol. 8 | No. 1 | Pages 14-21)
Alex Ward, H. Michael Arrighi, Shannon Michels, Jesse M. Cedarbaum
Screening and treatment for Alzheimer's disease: Predicting population-level outcomes
January 2012 (Vol. 8 | No. 1 | Pages 31-38)
Nicolas M. Furiak, Kristin Kahle-Wrobleski, Christopher Callahan, Timothy M. Klein, Robert W. Klein, Eric R. Siemers

Vascular risk factors, apolipoprotein E, and hippocampal decline on magnetic resonance imaging over a 10-year follow-up
16 January 2012
Tom den Heijer, Fedde van der Lijn, Arfan Ikram, Peter J. Koudstaal, Aad van der Lugt, Gabriel P. Krestin, Henri A. Vrooman, Albert Hofman, Wiro J. Niessen, Monique M.B. Breteler
Abstract: Background: Decline of hippocampal volume on magnetic resonance imaging (MRI) may be considered as a surrogate biomarker of accumulating Alzheimer disease (AD) pathology. Previously, we show...
Are dental X-rays causing Alzheimer’s? Ten reasons to take a closer look
09 January 2012
Caroline Rodgers
The speed with which Alzheimer’s disease has become a killer worldwide argues against a complex etiology because the more factors required for an outcome, the more difficult it is to meet all of the c...
Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ɛ4 carriers
09 January 2012
Sean P. Deeny, Jeanna Winchester, Kathryn Nichol, Stephen M. Roth, Joseph C. Wu, Malcolm Dick, Carl W. Cotman
Abstract: Background: The possibility that ɛ4 may modulate the effects of fitness in the brain remains controversial. The present exploratory FDG-PET study aimed to better understand the relationship ...
Association of environmental tobacco smoke with dementia and Alzheimer’s disease among never smokers
26 December 2011
Ruoling Chen
Abstract: Background: Environmental tobacco smoke (ETS) is known to be harmful; however, its association with dementia remains controversial and with Alzheimer’s disease (AD) is unknown. Methods: Usin...
Some evolutionary perspectives on Alzheimer’s disease pathogenesis and pathology
05 December 2011
Daniel J. Glass, Steven E. Arnold
Abstract: There is increasing urgency to develop effective prevention and treatment for Alzheimer’s disease (AD) as the aging population swells. Yet, our understanding remains limited for the elementa...

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The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
May 2011 (Vol. 7 | No. 3 | Pages 263-269)
Guy M. McKhann, David S. Knopman, Howard Chertkow, Bradley T. Hyman, Clifford R. Jack, Claudia H. Kawas, William E. Klunk, Walter J. Koroshetz, Jennifer J. Manly, Richard Mayeux, Richard C. Mohs, John C. Morris, Martin N. Rossor, Philip Scheltens, Maria C. Carrillo, Bill Thies, Sandra Weintraub, Creighton H. Phelps
Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
May 2011 (Vol. 7 | No. 3 | Pages 257-262)
Clifford R. Jack, Marilyn S. Albert, David S. Knopman, Guy M. McKhann, Reisa A. Sperling, Maria C. Carrillo, Bill Thies, Creighton H. Phelps
The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
May 2011 (Vol. 7 | No. 3 | Pages 270-279)
Marilyn S. Albert, Steven T. DeKosky, Dennis Dickson, Bruno Dubois, Howard H. Feldman, Nick C. Fox, Anthony Gamst, David M. Holtzman, William J. Jagust, Ronald C. Petersen, Peter J. Snyder, Maria C. Carrillo, Bill Thies, Creighton H. Phelps
Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
May 2011 (Vol. 7 | No. 3 | Pages 280-292)
Reisa A. Sperling, Paul S. Aisen, Laurel A. Beckett, David A. Bennett, Suzanne Craft, Anne M. Fagan, Takeshi Iwatsubo, Clifford R. Jack, Jeffrey Kaye, Thomas J. Montine, Denise C. Park, Eric M. Reiman, Christopher C. Rowe, Eric Siemers, Yaakov Stern, Kristine Yaffe, Maria C. Carrillo, Bill Thies, Marcelle Morrison-Bogorad, Molly V. Wagster, Creighton H. Phelps
2011 Alzheimer’s disease facts and figures
March 2011 (Vol. 7 | No. 2 | Pages 208-244)
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The Alzheimer's Association is the leading, global voluntary health organization in Alzheimer care and support, and the largest private, nonprofit funder of Alzheimer research.

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